Intranasal immunization with an RBD-hemagglutinin fusion protein harnesses preexisting immunity to enhance antigen-specific responses

Intranasal vaccines are anticipated to be powerful tools for combating many infectious diseases, including SARS-CoV-2, because they induce not only systemic immunity but also mucosal immunity at the site of initial infection. However, they are generally inefficient in inducing an antigen-specific im...

Descripción completa

Detalles Bibliográficos
Autores principales: Kawai, Atsushi, Tokunoh, Nagisa, Kawahara, Eigo, Tamiya, Shigeyuki, Okamura, Shinya, Ono, Chikako, Anindita, Jessica, Tanaka, Hiroki, Akita, Hidetaka, Yamasaki, Sho, Kunisawa, Jun, Okamoto, Toru, Matsuura, Yoshiharu, Hirai, Toshiro, Yoshioka, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688985/
https://www.ncbi.nlm.nih.gov/pubmed/38038133
http://dx.doi.org/10.1172/JCI166827

Ejemplares similares

Ejemplares similares