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Endothelial ADAM10 utilization defines a molecular pathway of vascular injury in mice with bacterial sepsis
The endothelium plays a critical role in the host response to infection and has been a focus of investigation in sepsis. While it is appreciated that intravascular thrombus formation, severe inflammation, and loss of endothelial integrity impair tissue oxygenation during sepsis, the precise molecula...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688991/ https://www.ncbi.nlm.nih.gov/pubmed/37788087 http://dx.doi.org/10.1172/JCI168450 |