Cargando…

Altering the Trajectory of Perfusion-Diffusion Deficits Using A BDNF Mimetic Acutely After TBI is Associated with Improved Functional Connectivity

Traumatic brain injury (TBI) results in metabolic deficits and functionally compromised tissue. The BDNF mimetic R13 has a significant positive effect on both tissue metabolism and behavioral outcome after TBI, indicating a promising therapeutic. To understand the mechanism of action for this interv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smith, Gregory, Thapak, Pavan, Paydar, Afshin, Ying, Zhe, Gomez-Pinilla, Fernando, Harris, Neil G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689006/ https://www.ncbi.nlm.nih.gov/pubmed/38037566 http://dx.doi.org/10.60124/j.pneuro.2023.10.07

Ejemplares similares

COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI)
por: Smith, Douglas H., et al.
Publicado: (2021)

Thioredoxin-Mimetic-Peptides Protect Cognitive Function after Mild Traumatic Brain Injury (mTBI)
por: Baratz-Goldstein, Renana, et al.
Publicado: (2016)

Deficits in Visual System Functional Connectivity after Blast‐Related Mild TBI are Associated with Injury Severity and Executive Dysfunction
por: Gilmore, Casey S., et al.
Publicado: (2016)

Quantified MRI and cognition in TBI with diffuse and focal damage()
por: Levine, Brian, et al.
Publicado: (2013)

Sex differences in orbitofrontal connectivity in male and female veterans with TBI
por: McGlade, Erin, et al.
Publicado: (2015)

iDISCO Inferno: Mapping Connectivity Changes Following TBI
por: Lau, Lauren A., et al.
Publicado: (2023)

Electroacupuncture improves TBI dysfunction by targeting HDAC overexpression and BDNF-associated Akt/GSK-3β signaling
por: Hung, Shih-Ya, et al.
Publicado: (2022)

Optimal cerebral perfusion pressure via transcranial Doppler in TBI: application of robotic technology
por: Zeiler, Frederick A., et al.
Publicado: (2018)

Post mTBI fatigue is associated with abnormal brain functional connectivity
por: Nordin, Love Engström, et al.
Publicado: (2016)

Brief mindfulness training alters causal brain connections in mTBI
por: Tang, Rongxiang, et al.
Publicado: (2015)

Antidepressant Effect of Dimeric Dipeptide GSB-106, an Original Low-Molecular-Weight Mimetic of BDNF
por: Seredenin, S.B., et al.
Publicado: (2013)

Cerebral Perfusion Effects of Cognitive Training and Transcranial Direct Current Stimulation in Mild-Moderate TBI
por: Quinn, Davin K., et al.
Publicado: (2020)

A Machine Learning Enhanced Mechanistic Simulation Framework for Functional Deficit Prediction in TBI
por: Schroder, Anna, et al.
Publicado: (2021)

Editorial: Evidence-Based Anti-Inflammatory, Anti-Hypoperfusion and Anti-Anxiety/Insomnia Therapies Show Promises for TBI-Induced Post-Traumatic Symptoms and Cognitive Deficits: Advances in Diagnosis and Treatment of TBI-Induced Neurodegeneration and Cognitive Deficits
por: Xing, Guoqiang, et al.
Publicado: (2021)

Dysfunctional Autism Risk Genes Cause Circuit-Specific Connectivity Deficits With Distinct Developmental Trajectories
por: Zerbi, Valerio, et al.
Publicado: (2018)

Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome
por: Parrini, Martina, et al.
Publicado: (2017)

Characterizing Brain Structures and Remodeling after TBI Based on Information Content, Diffusion Entropy
por: Fozouni, Niloufar, et al.
Publicado: (2013)

Altered Effective Connectivity of Hippocampus-Dependent Episodic Memory Network in mTBI Survivors
por: Yan, Hao, et al.
Publicado: (2016)

Dynamic association between perfusion and white matter integrity across time since injury in Veterans with history of TBI
por: Clark, Alexandra L., et al.
Publicado: (2016)

Robust training attenuates TBI-induced deficits in reference and working memory on the radial 8-arm maze
por: Sebastian, Veronica, et al.
Publicado: (2013)

Perfusion deficits in thrombolysis-treated acute ischemic stroke patients with negative or positive diffusion-weighted imaging
por: Zhu, Cuiting, et al.
Publicado: (2023)

Perfusion Deficits and Functional Connectivity Alterations in Memory-Related Regions of Patients with Post-Traumatic Stress Disorder
por: Liu, Yang, et al.
Publicado: (2016)

Antidepressant-like Effects of BDNF and NGF Individual Loop Dipeptide Mimetics Depend on the Signal Transmission Patterns Associated with Trk
por: Mezhlumyan, Armen G., et al.
Publicado: (2022)

BDNF Genotype Modulates Resting Functional Connectivity in Children
por: Thomason, Moriah E., et al.
Publicado: (2009)

The Brain–Liver Connection Between BDNF and Glucose Control
por: Jo, Young-Hwan, et al.
Publicado: (2013)

A promising connection between BDNF and Alzheimer’s disease
por: Giuffrida, Maria Laura, et al.
Publicado: (2018)

mTBI-Induced Systemic Vascular Dysfunction in a Mouse mTBI Model
por: Lv, Weizhen, et al.
Publicado: (2022)

Impact of Sociodemographic, Premorbid, and Injury-Related Factors on Patient-Reported Outcome Trajectories after Traumatic Brain Injury (TBI)
por: von Steinbuechel, Nicole, et al.
Publicado: (2023)

Apolipoprotein E mimetic peptide protects against diffuse brain injury
por: Zhao, Yaning, et al.
Publicado: (2014)

Alterations of cerebral perfusion and functional brain connectivity in medication‐naïve male adults with attention‐deficit/hyperactivity disorder
por: Tan, Ya‐Wen, et al.
Publicado: (2019)

Role of tDCS in TBI
por: Verma, Rohit
Publicado: (2022)

Dimeric mimetic of BDNF loop 4 promotes survival of serum-deprived cell through TrkB-dependent apoptosis suppression
por: Zainullina, L. F., et al.
Publicado: (2021)

A Low-Molecular-Weight BDNF Mimetic, Dipeptide GSB-214, Prevents Memory Impairment in Rat Models of Alzheimer’s Disease
por: Povarnina, P. Yu., et al.
Publicado: (2022)

Geometric diffusion of quantum trajectories
por: Yang, Fan, et al.
Publicado: (2015)

Diffusion Tensor Imaging (DTI) Findings Following Pediatric Non-Penetrating TBI: A Meta-Analysis
por: Roberts, R. M., et al.
Publicado: (2014)

Dynamic changes in hippocampal diffusion and kurtosis metrics following experimental mTBI correlate with glial reactivity
por: Braeckman, Kim, et al.
Publicado: (2019)

Brain Temperature Influences Intracranial Pressure and Cerebral Perfusion Pressure After Traumatic Brain Injury: A CENTER-TBI Study
por: Birg, Tatiana, et al.
Publicado: (2021)

Early deviation from normal structural connectivity: A novel intrinsic severity score for mild TBI
por: Taylor, Peter Neal, et al.
Publicado: (2020)

Associations of mTBI and post-traumatic stress to amygdala structure and functional connectivity in military Service Members
por: Gimbel, Sarah I., et al.
Publicado: (2023)

Is Helping Really Helping? Health-Related Quality of Life after TBI Predicting Caregiver Depression Symptom Trajectories in Latin America
por: Ohayagha, Chimdindu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_p1pdd03l751heujdeubq40k5l9