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Adult Pancreatoblastoma: An Uncommon Pancreatic Malignancy

In this report we present a rare case of pancreatoblastoma in an adult patient. Whilst they are amongst the most common malignant pancreatic tumours in children, presentations in adults are exceedingly rare, with a small number of reported cases. Its presentation is often non-specific in terms of cl...

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Detalles Bibliográficos
Autores principales: Hussain, Aroosh, Farrukh, Jawaad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689026/
https://www.ncbi.nlm.nih.gov/pubmed/38046486
http://dx.doi.org/10.7759/cureus.48063
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author Hussain, Aroosh
Farrukh, Jawaad
author_facet Hussain, Aroosh
Farrukh, Jawaad
author_sort Hussain, Aroosh
collection PubMed
description In this report we present a rare case of pancreatoblastoma in an adult patient. Whilst they are amongst the most common malignant pancreatic tumours in children, presentations in adults are exceedingly rare, with a small number of reported cases. Its presentation is often non-specific in terms of clinical examination, and subsequent imaging can show similar findings to those seen in benign neoplasms. This report highlights the difficulty of achieving a diagnosis and subsequent treatment of such an uncommon disease. Biopsy and resultant histology are essential in diagnosis and surgical resection remains the preferred modality of treatment. However, the use of chemotherapy and its efficacy in adults remains unclear, and the prognosis documented in existing literature for adults is worse when compared to paediatric presentations. This case emphasises the need to consider pancreatoblastoma as a differential diagnosis when suspecting pancreatic or abdominal malignancies to achieve early detection and diagnosis, in order to provide optimal treatment and improve patient outcomes.
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spelling pubmed-106890262023-12-01 Adult Pancreatoblastoma: An Uncommon Pancreatic Malignancy Hussain, Aroosh Farrukh, Jawaad Cureus Radiology In this report we present a rare case of pancreatoblastoma in an adult patient. Whilst they are amongst the most common malignant pancreatic tumours in children, presentations in adults are exceedingly rare, with a small number of reported cases. Its presentation is often non-specific in terms of clinical examination, and subsequent imaging can show similar findings to those seen in benign neoplasms. This report highlights the difficulty of achieving a diagnosis and subsequent treatment of such an uncommon disease. Biopsy and resultant histology are essential in diagnosis and surgical resection remains the preferred modality of treatment. However, the use of chemotherapy and its efficacy in adults remains unclear, and the prognosis documented in existing literature for adults is worse when compared to paediatric presentations. This case emphasises the need to consider pancreatoblastoma as a differential diagnosis when suspecting pancreatic or abdominal malignancies to achieve early detection and diagnosis, in order to provide optimal treatment and improve patient outcomes. Cureus 2023-10-31 /pmc/articles/PMC10689026/ /pubmed/38046486 http://dx.doi.org/10.7759/cureus.48063 Text en Copyright © 2023, Hussain et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiology
Hussain, Aroosh
Farrukh, Jawaad
Adult Pancreatoblastoma: An Uncommon Pancreatic Malignancy
title Adult Pancreatoblastoma: An Uncommon Pancreatic Malignancy
title_full Adult Pancreatoblastoma: An Uncommon Pancreatic Malignancy
title_fullStr Adult Pancreatoblastoma: An Uncommon Pancreatic Malignancy
title_full_unstemmed Adult Pancreatoblastoma: An Uncommon Pancreatic Malignancy
title_short Adult Pancreatoblastoma: An Uncommon Pancreatic Malignancy
title_sort adult pancreatoblastoma: an uncommon pancreatic malignancy
topic Radiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689026/
https://www.ncbi.nlm.nih.gov/pubmed/38046486
http://dx.doi.org/10.7759/cureus.48063
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