Elevated level of PLRG1 is critical for the proliferation and maintenance of genome stability of tumor cells

Pleiotropic regulator 1 (PLRG1), a highly conserved element in the spliceosome, can form a NineTeen Complex (NTC) with Prp19, SPF27, and CDC5L. This complex plays crucial roles in both pre-mRNA splicing and DNA repair processes. Here, we provide evidence that PLRG1 has a multifaceted impact on cance...

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Detalles Bibliográficos
Autores principales: Choi, Hyunji, Kang, Moonkyung, Lee, Kee-Ho, Kim, Yeon-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689083/
https://www.ncbi.nlm.nih.gov/pubmed/37817442
http://dx.doi.org/10.5483/BMBRep.2023-0162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689083/
https://www.ncbi.nlm.nih.gov/pubmed/37817442
http://dx.doi.org/10.5483/BMBRep.2023-0162

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