Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity

Nedd4-2 is an E3 ubiquitin ligase in which missense mutation is related to familial epilepsy, indicating its critical role in regulating neuronal network activity. However, Nedd4-2 substrates involved in neuronal network function have yet to be identified. Using mouse lines lacking Nedd4-1 and Nedd4...

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Detalles Bibliográficos
Autores principales: Altas, Bekir, Rhee, Hong-Jun, Ju, Anes, Solís, Hugo Cruces, Karaca, Samir, Winchenbach, Jan, Kaplan-Arabaci, Oykum, Schwark, Manuela, Ambrozkiewicz, Mateusz C., Lee, ChungKu, Spieth, Lena, Wieser, Georg L., Chaugule, Viduth K., Majoul, Irina, Hassan, Mohamed A., Goel, Rashi, Wojcik, Sonja M., Koganezawa, Noriko, Hanamura, Kenji, Rotin, Daniela, Pichler, Andrea, Mitkovski, Miso, de Hoz, Livia, Poulopoulos, Alexandros, Urlaub, Henning, Jahn, Olaf, Saher, Gesine, Brose, Nils, Rhee, JeongSeop, Kawabe, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689203/
https://www.ncbi.nlm.nih.gov/pubmed/38032389
http://dx.doi.org/10.1083/jcb.201902050

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