Simvastatin/hydrogel-loaded 3D-printed titanium alloy scaffolds suppress osteosarcoma via TF/NOX2-associated ferroptosis while repairing bone defects

Postoperative anatomical reconstruction and prevention of local recurrence after tumor resection are two vital clinical challenges in osteosarcoma treatment. A three-dimensional (3D)-printed porous Ti6Al4V scaffold (3DTi) is an ideal material for reconstructing critical bone defects with numerous ad...

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Detalles Bibliográficos
Autores principales: Jing, Zehao, Yuan, Wanqiong, Wang, Jiedong, Ni, Renhua, Qin, Yu, Mao, Zhinan, Wei, Feng, Song, Chunli, Zheng, Yufeng, Cai, Hong, Liu, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689208/
https://www.ncbi.nlm.nih.gov/pubmed/38045570
http://dx.doi.org/10.1016/j.bioactmat.2023.11.001

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