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Adjusting perioperative methadone dose for elderly and fragile hip fracture patients (MetaHip-trial) – A statistical analysis plan for an adaptive dose-finding trial

BACKGROUND: The elderly population is expanding globally. This gives numerous challenges especially regarding hip fracture patients. In the US alone over 300.000 hip fracture patients are treated each year, and a large amount of those develop opoid addiction. Hip fractures require surgical intervent...

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Detalles Bibliográficos
Autores principales:	Pedersen, Andreas Kristian, Nygaard, Kevin Heebøll, Petersen, Sofie Ronja, Specht, Kirsten, Strøm, Thomas, Moos, Caroline Margaret, Skjøt-Arkil, Helene, Schønnemann, Jesper Ougaard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689264/ https://www.ncbi.nlm.nih.gov/pubmed/38047142 http://dx.doi.org/10.1016/j.conctc.2023.101228

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