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Contribution of the SOS response and the DNA repair systems to norfloxacin induced mutations in E. coli

Antibiotic-resistant bacteria severely threaten human health. Besides spontaneous mutations generated by endogenous factors, the resistance might also originate from mutations induced by certain antibiotics, such as the fluoroquinolones. Such antibiotics increase the genome-wide mutation rate by int...

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Detalles Bibliográficos
Autores principales: Lin, Tongtong, Pan, Jiao, Gregory, Colin, Wang, Yaohai, Tincher, Clayton, Rivera, Caitlyn, Lynch, Michael, Long, Hongan, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689325/
https://www.ncbi.nlm.nih.gov/pubmed/38045542
http://dx.doi.org/10.1007/s42995-023-00185-y