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Delayed vaccine-induced CD8(+) T cell expansion by topoisomerase I inhibition mediates enhanced CD70-dependent tumor eradication

BACKGROUND: The survival of patients with cervical cancer who are treated with cisplatin in conjunction with the topoisomerase I inhibitor topotecan is enhanced when compared with patients treated with only one of these chemotherapeutics. Moreover, cisplatin-based and T cell-based immunotherapy have...

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Detalles Bibliográficos
Autores principales:	van der Sluis, Tetje C, van Haften, Floortje J, van Duikeren, Suzanne, Pardieck, Iris N, de Graaf, J Fréderique, Vleeshouwers, Ward, van der Maaden, Koen, Melief, Cornelis J M, van der Burg, Sjoerd H, Arens, Ramon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689370/ https://www.ncbi.nlm.nih.gov/pubmed/38030302 http://dx.doi.org/10.1136/jitc-2023-007158

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