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Randomised, placebo-controlled, phase 3 trial of the effect of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) on colorectal cancer recurrence and survival after surgery for resectable liver metastases: EPA for Metastasis Trial 2 (EMT2) study protocol

INTRODUCTION: There remains an unmet need for safe and cost-effective adjunctive treatment of advanced colorectal cancer (CRC). The omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) is safe, well-tolerated and has anti-inflammatory as well as antineoplastic properties. A phase 2 randomi...

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Detalles Bibliográficos
Autores principales: Hull, Mark A, Ow, Pei Loo, Ruddock, Sharon, Brend, Tim, Smith, Alexandra F, Marshall, Helen, Song, Mingyang, Chan, Andrew T, Garrett, Wendy S, Yilmaz, Omer, Drew, David A, Collinson, Fiona, Cockbain, Andrew J, Jones, Robert, Loadman, Paul M, Hall, Peter S, Moriarty, Catherine, Cairns, David A, Toogood, Giles J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689403/
https://www.ncbi.nlm.nih.gov/pubmed/38030258
http://dx.doi.org/10.1136/bmjopen-2023-077427