Detection of NTRK fusions by RNA-based nCounter is a feasible diagnostic methodology in a real-world scenario for non-small cell lung cancer assessment

NTRK1, 2, and 3 fusions are important therapeutic targets for NSCLC patients, but their prevalence in South American admixed populations needs to be better explored. NTRK fusion detection in small biopsies is a challenge, and distinct methodologies are used, such as RNA-based next-generation sequenc...

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Detalles Bibliográficos
Autores principales: de Oliveira Cavagna, Rodrigo, de Andrade, Edilene Santos, Tadin Reis, Monise, de Paula, Flávia Escremim, Noriz Berardinelli, Gustavo, Bonatelli, Murilo, Ramos Teixeira, Gustavo, Garbe Zaniolo, Beatriz, Mourão Dias, Josiane, da Silva, Flávio Augusto Ferreira, Baston Silva, Carlos Eduardo, Xavier Reis, Marina, Lopes Maia, Erika, de Alencar, Thainara Santos, Jacinto, Alexandre Arthur, da Nóbrega Oliveira, Rachid Eduardo Noleto, Molina-Vila, Miguel A., Ferro Leal, Letícia, Reis, Rui Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689426/
https://www.ncbi.nlm.nih.gov/pubmed/38036758
http://dx.doi.org/10.1038/s41598-023-48613-4

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