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Marine toxin domoic acid alters nitrogen cycling in sediments
As a red tide algal toxin with intense neurotoxicity distributed worldwide, domoic acid (DA) has attracted increasing concerns. In this work, the integrative analysis of metagenome and metabolome are applied to investigate the impact of DA on nitrogen cycling in coastal sediments. Here we show that...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689436/ https://www.ncbi.nlm.nih.gov/pubmed/38036528 http://dx.doi.org/10.1038/s41467-023-43265-4 |
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author | Li, Zelong Wang, Jing Yue, Hao Du, Miaomiao Jin, Yuan Fan, Jingfeng |
author_facet | Li, Zelong Wang, Jing Yue, Hao Du, Miaomiao Jin, Yuan Fan, Jingfeng |
author_sort | Li, Zelong |
collection | PubMed |
description | As a red tide algal toxin with intense neurotoxicity distributed worldwide, domoic acid (DA) has attracted increasing concerns. In this work, the integrative analysis of metagenome and metabolome are applied to investigate the impact of DA on nitrogen cycling in coastal sediments. Here we show that DA can act as a stressor to induce the variation of nitrogen (N) cycling by altering the abundance of functional genes and electron supply. Moreover, microecology theory revealed that DA can increase the role of deterministic assembly in microbial dynamic succession, resulting in the shift of niches and, ultimately, the alteration in N cycling. Notably, denitrification and Anammox, the important process for sediment N removal, are markedly limited by DA. Also, variation of N cycling implies the modification in cycles of other associated elements. Overall, DA is capable of ecosystem-level effects, which require further evaluation of its potential cascading effects. |
format | Online Article Text |
id | pubmed-10689436 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-106894362023-12-02 Marine toxin domoic acid alters nitrogen cycling in sediments Li, Zelong Wang, Jing Yue, Hao Du, Miaomiao Jin, Yuan Fan, Jingfeng Nat Commun Article As a red tide algal toxin with intense neurotoxicity distributed worldwide, domoic acid (DA) has attracted increasing concerns. In this work, the integrative analysis of metagenome and metabolome are applied to investigate the impact of DA on nitrogen cycling in coastal sediments. Here we show that DA can act as a stressor to induce the variation of nitrogen (N) cycling by altering the abundance of functional genes and electron supply. Moreover, microecology theory revealed that DA can increase the role of deterministic assembly in microbial dynamic succession, resulting in the shift of niches and, ultimately, the alteration in N cycling. Notably, denitrification and Anammox, the important process for sediment N removal, are markedly limited by DA. Also, variation of N cycling implies the modification in cycles of other associated elements. Overall, DA is capable of ecosystem-level effects, which require further evaluation of its potential cascading effects. Nature Publishing Group UK 2023-11-30 /pmc/articles/PMC10689436/ /pubmed/38036528 http://dx.doi.org/10.1038/s41467-023-43265-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Li, Zelong Wang, Jing Yue, Hao Du, Miaomiao Jin, Yuan Fan, Jingfeng Marine toxin domoic acid alters nitrogen cycling in sediments |
title | Marine toxin domoic acid alters nitrogen cycling in sediments |
title_full | Marine toxin domoic acid alters nitrogen cycling in sediments |
title_fullStr | Marine toxin domoic acid alters nitrogen cycling in sediments |
title_full_unstemmed | Marine toxin domoic acid alters nitrogen cycling in sediments |
title_short | Marine toxin domoic acid alters nitrogen cycling in sediments |
title_sort | marine toxin domoic acid alters nitrogen cycling in sediments |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689436/ https://www.ncbi.nlm.nih.gov/pubmed/38036528 http://dx.doi.org/10.1038/s41467-023-43265-4 |
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