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SARS-CoV-2 nsp3 and nsp4 are minimal constituents of a pore spanning replication organelle

Coronavirus replication is associated with the remodeling of cellular membranes, resulting in the formation of double-membrane vesicles (DMVs). A DMV-spanning pore was identified as a putative portal for viral RNA. However, the exact components and the structure of the SARS-CoV-2 DMV pore remain to...

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Detalles Bibliográficos
Autores principales: Zimmermann, Liv, Zhao, Xiaohan, Makroczyova, Jana, Wachsmuth-Melm, Moritz, Prasad, Vibhu, Hensel, Zach, Bartenschlager, Ralf, Chlanda, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689437/
https://www.ncbi.nlm.nih.gov/pubmed/38036567
http://dx.doi.org/10.1038/s41467-023-43666-5