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SARS-CoV-2 nsp3 and nsp4 are minimal constituents of a pore spanning replication organelle
Coronavirus replication is associated with the remodeling of cellular membranes, resulting in the formation of double-membrane vesicles (DMVs). A DMV-spanning pore was identified as a putative portal for viral RNA. However, the exact components and the structure of the SARS-CoV-2 DMV pore remain to...
Autores principales: | Zimmermann, Liv, Zhao, Xiaohan, Makroczyova, Jana, Wachsmuth-Melm, Moritz, Prasad, Vibhu, Hensel, Zach, Bartenschlager, Ralf, Chlanda, Petr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689437/ https://www.ncbi.nlm.nih.gov/pubmed/38036567 http://dx.doi.org/10.1038/s41467-023-43666-5 |
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