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The poxvirus F17 protein counteracts mitochondrially orchestrated antiviral responses

Poxviruses are unusual DNA viruses that replicate in the cytoplasm. To do so, they encode approximately 100 immunomodulatory proteins that counteract cytosolic nucleic acid sensors such as cGAMP synthase (cGAS) along with several other antiviral response pathways. Yet most of these immunomodulators...

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Detalles Bibliográficos
Autores principales: Meade, Nathan, Toreev, Helen K., Chakrabarty, Ram P., Hesser, Charles R., Park, Chorong, Chandel, Navdeep S., Walsh, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689448/
https://www.ncbi.nlm.nih.gov/pubmed/38036506
http://dx.doi.org/10.1038/s41467-023-43635-y

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