Signet cell rectal carcinoma with prostatic involvement detected by FAPI-04 PET-MRI fusion

A 60-year-old male patient diagnosed with mucinous adenocarcinoma of lower third of rectum underwent abdominoperineal resection and permanent colostomy followed by adjuvant chemotherapy. Response evaluation with F-18 FDG PET-CT showed a complete metabolic response. After 6 months, CEA levels started...

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Autores principales: Prashanth, K. Arun, Jain, Deepti, Manikandan, R., Kalyan, Suman, Velayutham, Vimalraj, Surendran, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689635/
https://www.ncbi.nlm.nih.gov/pubmed/38036687
http://dx.doi.org/10.1186/s41824-023-00183-4
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author Prashanth, K. Arun
Jain, Deepti
Manikandan, R.
Kalyan, Suman
Velayutham, Vimalraj
Surendran, R.
author_facet Prashanth, K. Arun
Jain, Deepti
Manikandan, R.
Kalyan, Suman
Velayutham, Vimalraj
Surendran, R.
author_sort Prashanth, K. Arun
collection PubMed
description A 60-year-old male patient diagnosed with mucinous adenocarcinoma of lower third of rectum underwent abdominoperineal resection and permanent colostomy followed by adjuvant chemotherapy. Response evaluation with F-18 FDG PET-CT showed a complete metabolic response. After 6 months, CEA levels started increasing and clinically a recurrence was suspected. A restaging FDG PET-CT showed no obvious malignant disease. Patient presented again within a month with complaints of urinary retention and haematuria. CEA levels were further elevated, and Ga-68 FAPI-04 (FAPI) PET-CT was performed. FAPI PET-CT revealed prostatic and seminal vesicle disease involvement. Additionally, an MRI of pelvis was done and fused with FAPI PET for confirmation of prostatic involvement.
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spelling pubmed-106896352023-12-02 Signet cell rectal carcinoma with prostatic involvement detected by FAPI-04 PET-MRI fusion Prashanth, K. Arun Jain, Deepti Manikandan, R. Kalyan, Suman Velayutham, Vimalraj Surendran, R. Eur J Hybrid Imaging Case Report A 60-year-old male patient diagnosed with mucinous adenocarcinoma of lower third of rectum underwent abdominoperineal resection and permanent colostomy followed by adjuvant chemotherapy. Response evaluation with F-18 FDG PET-CT showed a complete metabolic response. After 6 months, CEA levels started increasing and clinically a recurrence was suspected. A restaging FDG PET-CT showed no obvious malignant disease. Patient presented again within a month with complaints of urinary retention and haematuria. CEA levels were further elevated, and Ga-68 FAPI-04 (FAPI) PET-CT was performed. FAPI PET-CT revealed prostatic and seminal vesicle disease involvement. Additionally, an MRI of pelvis was done and fused with FAPI PET for confirmation of prostatic involvement. Springer International Publishing 2023-12-01 /pmc/articles/PMC10689635/ /pubmed/38036687 http://dx.doi.org/10.1186/s41824-023-00183-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Case Report
Prashanth, K. Arun
Jain, Deepti
Manikandan, R.
Kalyan, Suman
Velayutham, Vimalraj
Surendran, R.
Signet cell rectal carcinoma with prostatic involvement detected by FAPI-04 PET-MRI fusion
title Signet cell rectal carcinoma with prostatic involvement detected by FAPI-04 PET-MRI fusion
title_full Signet cell rectal carcinoma with prostatic involvement detected by FAPI-04 PET-MRI fusion
title_fullStr Signet cell rectal carcinoma with prostatic involvement detected by FAPI-04 PET-MRI fusion
title_full_unstemmed Signet cell rectal carcinoma with prostatic involvement detected by FAPI-04 PET-MRI fusion
title_short Signet cell rectal carcinoma with prostatic involvement detected by FAPI-04 PET-MRI fusion
title_sort signet cell rectal carcinoma with prostatic involvement detected by fapi-04 pet-mri fusion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689635/
https://www.ncbi.nlm.nih.gov/pubmed/38036687
http://dx.doi.org/10.1186/s41824-023-00183-4
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