Unravelling transcriptomic complexity in breast cancer through modulation of DARPP-32 expression and signalling pathways

DARPP-32 is a key regulator of protein-phosphatase-1 (PP-1) and protein kinase A (PKA), with its function dependent upon its phosphorylation state. We previously identified DKK1 and GRB7 as genes with linked expression using Artificial Neural Network (ANN) analysis; here, we determine protein expres...

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Detalles Bibliográficos
Autores principales: Saidy, Behnaz, Vasan, Richa, Durant, Rosie, Greener, Megan-Rose, Immanuel, Adelynn, Green, Andrew R., Rakha, Emad, Ellis, Ian, Ball, Graham, Martin, Stewart G., Storr, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689788/
https://www.ncbi.nlm.nih.gov/pubmed/38036593
http://dx.doi.org/10.1038/s41598-023-48198-y

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