The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology

Ample evidence has suggested the stress etiology of depression, but the underlying mechanism is not fully understood yet. Here, we report that chronic social defeat stress (CSDS) attenuates the excitatory output of the claustrum (CLA) to the prelimbic cortex (PL) through the dynorphin/κ-opioid recep...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Jun, Zan, Gui-Ying, Xu, Cenglin, Li, Xue-Ping, Shu, Xuelian, Yao, Song-Yu, Xu, Xiao-Shan, Qiu, Xiaoyun, Chen, Yexiang, Jin, Kai, Zhou, Qi-Xin, Ye, Jia-Yu, Wang, Yi, Xu, Lin, Chen, Zhong, Liu, Jing-Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689794/
https://www.ncbi.nlm.nih.gov/pubmed/38036497
http://dx.doi.org/10.1038/s41467-023-43636-x

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