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Hyperglycolysis in endothelial cells drives endothelial injury and microvascular alterations in peritoneal dialysis

BACKGROUND: Endothelial cell (EC) dysfunction leading to microvascular alterations is a hallmark of technique failure in peritoneal dialysis (PD). However, the mechanisms underlying EC dysfunction in PD are poorly defined. METHODS: We combined RNA sequencing with metabolite set analysis to character...

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Detalles Bibliográficos
Autores principales: Si, Zekun, Su, Wenyan, Zhou, Zhuoyu, Li, Jinjin, Su, Cailing, Zhang, Ying, Hu, Zuoyu, Huang, Zhijie, Zhou, Hong, Cong, Ansheng, Zhou, Zhanmei, Cao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689974/
https://www.ncbi.nlm.nih.gov/pubmed/38037461
http://dx.doi.org/10.1002/ctm2.1498