Tamoxifen Response at Single-Cell Resolution in Estrogen Receptor–Positive Primary Human Breast Tumors

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PURPOSE: In estrogen receptor–positive (ER(+))/HER2(−) breast cancer, multiple measures of intratumor heterogeneity are associated with a worse response to endocrine therapy. We sought to develop a novel experimental model to measure heterogeneity in response to tamoxifen treatment in primary breast...

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Detalles Bibliográficos
Autores principales: Kim, Hyunsoo, Whitman, Austin A., Wisniewska, Kamila, Kakati, Rasha T., Garcia-Recio, Susana, Calhoun, Benjamin C., Franco, Hector L., Perou, Charles M., Spanheimer, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690085/
https://www.ncbi.nlm.nih.gov/pubmed/37747807
http://dx.doi.org/10.1158/1078-0432.CCR-23-1248
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