Upregulation of Indoleamine 2,3-Dioxygenase 1 in Tumor Cells and Tertiary Lymphoid Structures is a Hallmark of Inflamed Non–Small Cell Lung Cancer

PURPOSE: Overexpression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase 1 (IDO1) has been reported in several tumor types, including non–small cell lung cancer (NSCLC), and has been shown to promote tumor-immune evasion and inhibit T-cell activation through increased tryptophan deg...

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Detalles Bibliográficos
Autores principales: Bessede, Alban, Peyraud, Florent, Le Moulec, Sylvestre, Cousin, Sophie, Cabart, Mathilde, Chomy, François, Rey, Christophe, Lara, Oren, Odin, Ophélie, Nafia, Imane, Guegan, Jean-Philippe, Italiano, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690088/
https://www.ncbi.nlm.nih.gov/pubmed/37756581
http://dx.doi.org/10.1158/1078-0432.CCR-23-1928

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