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Fibroblast Activation Protein-Targeted Radioligand Therapy with (177)Lu-EB-FAPI for Metastatic Radioiodine-Refractory Thyroid Cancer: First-in-Human, Dose-Escalation Study

PURPOSE: Fibroblast activation protein (FAP) is a promising target for tumor treatment. In this study, we aimed to investigate the safety and efficacy of the albumin binder-conjugated FAP-targeted radiopharmaceutical, (177)Lu-EB-FAPI ((177)Lu-LNC1004), in patients with metastatic radioiodine-refract...

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Detalles Bibliográficos
Autores principales:	Fu, Hao, Huang, Jingxiong, Zhao, Tianzhi, Wang, Hongjian, Chen, Yuhang, Xu, Weizhi, Pang, Yizhen, Guo, Wei, Sun, Long, Wu, Hua, Xu, Pengfei, Su, Bishan, Zhang, Jingjing, Chen, Xiaoyuan, Chen, Haojun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Clinical Trials: Targeted Therapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690094/ https://www.ncbi.nlm.nih.gov/pubmed/37801296 http://dx.doi.org/10.1158/1078-0432.CCR-23-1983

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