Cargando…

Genome-Wide Association and Two-Sample Mendelian Randomization Analyses of Plasma Ghrelin and Gastrointestinal Cancer Risk

BACKGROUND: Observational studies have suggested that the gut hormone ghrelin is an early marker of future risk of developing gastrointestinal cancer. However, whether ghrelin is a causal risk factor remains unclear. We conducted a genome-wide association study (GWAS) of plasma ghrelin and used Mend...

Descripción completa

Detalles Bibliográficos
Autores principales:	Larsson, Susanna C., Höijer, Jonas, Sun, Jing, Li, Xue, Burgess, Stephen, Michaëlsson, Karl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690139/ https://www.ncbi.nlm.nih.gov/pubmed/37791980 http://dx.doi.org/10.1158/1055-9965.EPI-23-0757

Ejemplares similares

Smoking and stroke: A mendelian randomization study
por: Larsson, Susanna C., et al.
Publicado: (2019)

IGF-1 and cardiometabolic diseases: a Mendelian randomisation study
por: Larsson, Susanna C., et al.
Publicado: (2020)

Serum magnesium levels and risk of coronary artery disease: Mendelian randomisation study
por: Larsson, Susanna C., et al.
Publicado: (2018)

Alcohol Consumption and Cardiovascular Disease: A Mendelian Randomization Study
por: Larsson, Susanna C., et al.
Publicado: (2020)

Genetically proxied milk consumption and risk of colorectal, bladder, breast, and prostate cancer: a two-sample Mendelian randomization study
por: Larsson, Susanna C., et al.
Publicado: (2020)

The impact and causal directions for the associations between diagnosis of ADHD, socioeconomic status, and intelligence by use of a bi-directional two-sample Mendelian randomization design
por: Michaëlsson, Madeleine, et al.
Publicado: (2022)

Circulating Alpha-Tocopherol Levels, Bone Mineral Density, and Fracture: Mendelian Randomization Study
por: Michaëlsson, Karl, et al.
Publicado: (2021)

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study
por: Larsson, Susanna C., et al.
Publicado: (2019)

Plasma proteins and onset of type 2 diabetes and diabetic complications: Proteome-wide Mendelian randomization and colocalization analyses
por: Yuan, Shuai, et al.
Publicado: (2023)

Sleep Duration and Stroke: Prospective Cohort Study and Mendelian Randomization Analysis
por: Titova, Olga E., et al.
Publicado: (2020)

Serum 25-Hydroxyvitamin D Concentrations and Major Depression: A Mendelian Randomization Study
por: Michaëlsson, Karl, et al.
Publicado: (2018)

Sleep duration and risk of overall and 22 site‐specific cancers: A Mendelian randomization study
por: Titova, Olga E., et al.
Publicado: (2020)

Smoking, alcohol consumption, and cancer: A mendelian randomisation study in UK Biobank and international genetic consortia participants
por: Larsson, Susanna C., et al.
Publicado: (2020)

Plasma Cortisol and Risk of Atrial Fibrillation: A Mendelian Randomization Study
por: Larsson, Susanna C, et al.
Publicado: (2021)

Serum Parathyroid Hormone, 25-Hydroxyvitamin D, and Risk of Alzheimer’s Disease: A Mendelian Randomization Study
por: Larsson, Susanna C., et al.
Publicado: (2018)

Iron Status and Cancer Risk in UK Biobank: A Two-Sample Mendelian Randomization Study
por: Yuan, Shuai, et al.
Publicado: (2020)

Smoking, alcohol consumption, and 24 gastrointestinal diseases: Mendelian randomization analysis
por: Yuan, Shuai, et al.
Publicado: (2023)

Selenium and cancer risk: Wide-angled Mendelian randomization analysis
por: Yuan, Shuai, et al.
Publicado: (2022)

Serum calcium and 25-hydroxyvitamin D in relation to longevity, cardiovascular disease and cancer: a Mendelian randomization study
por: Yuan, Shuai, et al.
Publicado: (2021)

Causal associations of thyroid function and dysfunction with overall, breast and thyroid cancer: A two-sample Mendelian randomization study
por: Yuan, Shuai, et al.
Publicado: (2020)

Causal associations of thyroid function and dysfunction with overall, breast and thyroid cancer: A two-sample Mendelian randomization study
por: Yuan, Shuai, et al.
Publicado: (2020)

Is Type 2 Diabetes Causally Associated With Cancer Risk? Evidence From a Two-Sample Mendelian Randomization Study
por: Yuan, Shuai, et al.
Publicado: (2020)

Appraisal of the causal effect of plasma caffeine on adiposity, type 2 diabetes, and cardiovascular disease: two sample mendelian randomisation study
por: Larsson, Susanna C, et al.
Publicado: (2023)

Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study
por: Yuan, Shuai, et al.
Publicado: (2020)

Fasting glucose, bone area and bone mineral density: a Mendelian randomisation study
por: Mitchell, Adam, et al.
Publicado: (2021)

Modifiable risk factors for epilepsy: A two‐sample Mendelian randomization study
por: Yuan, Shuai, et al.
Publicado: (2021)

Therapeutic targets for inflammatory bowel disease: proteome-wide Mendelian randomization and colocalization analyses
por: Chen, Jie, et al.
Publicado: (2023)

Fat mass and fat‐free mass in relation to cardiometabolic diseases: a two‐sample Mendelian randomization study
por: Larsson, S. C., et al.
Publicado: (2020)

Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization
por: Woolf, Benjamin, et al.
Publicado: (2023)

Insulin-like Growth Factor-1, Bone Mineral Density, and Fracture: A Mendelian Randomization Study
por: Yuan, Shuai, et al.
Publicado: (2021)

Assessing the protective role of allergic disease in gastrointestinal tract cancers using Mendelian randomization analysis
por: Yuan, Shuai, et al.
Publicado: (2020)

Gastrointestinal Consequences of Type 2 Diabetes Mellitus and Impaired Glycemic Homeostasis: A Mendelian Randomization Study
por: Chen, Jie, et al.
Publicado: (2023)

Bias due to participant overlap in two‐sample Mendelian randomization
por: Burgess, Stephen, et al.
Publicado: (2016)

Sleep-disordered breathing-related symptoms and risk of stroke: cohort study and Mendelian randomization analysis
por: Titova, Olga E., et al.
Publicado: (2021)

Estimating the Population Benefits of Blood Pressure Lowering: A Wide‐Angled Mendelian Randomization Study in UK Biobank
por: Higgins, Hannah, et al.
Publicado: (2021)

Plasma Phospholipid Fatty Acids, FADS1 and Risk of 15 Cardiovascular Diseases: A Mendelian Randomisation Study
por: Yuan, Shuai, et al.
Publicado: (2019)

Self‐reported symptoms of sleep‐disordered breathing and risk of cardiovascular diseases: Observational and Mendelian randomization findings
por: Titova, Olga E., et al.
Publicado: (2022)

Combined associations of body mass index and adherence to a Mediterranean-like diet with all-cause and cardiovascular mortality: A cohort study
por: Michaëlsson, Karl, et al.
Publicado: (2020)

Causal effect of renal function on venous thromboembolism: a two-sample Mendelian randomization investigation
por: Yuan, Shuai, et al.
Publicado: (2021)

Appraising the causal role of smoking in multiple diseases: A systematic review and meta-analysis of Mendelian randomization studies
por: Larsson, Susanna C., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c1eedavdknetm193md3fcust3e