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Monomeric α‐synuclein activates the plasma membrane calcium pump

Alpha‐synuclein (aSN) is a membrane‐associated and intrinsically disordered protein, well known for pathological aggregation in neurodegeneration. However, the physiological function of aSN is disputed. Pull‐down experiments have pointed to plasma membrane Ca(2+)‐ATPase (PMCA) as a potential interac...

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Detalles Bibliográficos
Autores principales: Kowalski, Antoni, Betzer, Cristine, Larsen, Sigrid Thirup, Gregersen, Emil, Newcombe, Estella A, Bermejo, Montaña Caballero, Bendtsen, Viktor Wisniewski, Diemer, Jorin, Ernstsen, Christina V, Jain, Shweta, Bou, Alicia Espiña, Langkilde, Annette Eva, Nejsum, Lene N, Klipp, Edda, Edwards, Robert, Kragelund, Birthe B, Jensen, Poul Henning, Nissen, Poul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690453/
https://www.ncbi.nlm.nih.gov/pubmed/37916890
http://dx.doi.org/10.15252/embj.2022111122

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