TOLLIP acts as a cargo adaptor to promote lysosomal degradation of aberrant ER membrane proteins

Endoplasmic reticulum (ER) proteostasis is maintained by various catabolic pathways. Lysosomes clear entire ER portions by ER‐phagy, while proteasomes selectively clear misfolded or surplus aberrant proteins by ER‐associated degradation (ERAD). Recently, lysosomes have also been implicated in the se...

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Detalles Bibliográficos
Autores principales: Hayashi, Yuki, Takatori, Sho, Warsame, Waleed Y, Tomita, Taisuke, Fujisawa, Takao, Ichijo, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690474/
https://www.ncbi.nlm.nih.gov/pubmed/37929762
http://dx.doi.org/10.15252/embj.2023114272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690474/
https://www.ncbi.nlm.nih.gov/pubmed/37929762
http://dx.doi.org/10.15252/embj.2023114272

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