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Fast HPLC-based affinity method to determine capsid titer and full/empty ratio of adeno-associated viral vectors

Recombinant adeno-associated viruses (rAAVs) are promising gene delivery vectors in the emerging field of in vivo gene therapies. To ensure their consistent quality during manufacturing and process development, multiple analytical techniques have been proposed for the characterization and quantifica...

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Detalles Bibliográficos
Autores principales:	Heckel, Jakob, Martinez, Andres, Elger, Carsten, Haindl, Markus, Leiss, Michael, Ruppert, Raphael, Williams, Chris, Hubbuch, Jürgen, Graf, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690635/ https://www.ncbi.nlm.nih.gov/pubmed/38046198 http://dx.doi.org/10.1016/j.omtm.2023.101148

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