Single-Molecule Detection of α-Synuclein Oligomers in Parkinson’s Disease Patients Using Nanopores

[Image: see text] α-Synuclein (α-Syn) is an intrinsically disordered protein whose aggregation in the brain has been significantly implicated in Parkinson’s disease (PD). Beyond the brain, oligomers of α-Synuclein are also found in cerebrospinal fluid (CSF) and blood, where the analysis of these agg...

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Detalles Bibliográficos
Autores principales: Liu, Yaxian, Wang, Xiaoyi, Campolo, Giulia, Teng, Xiangyu, Ying, Liming, Edel, Joshua B., Ivanov, Aleksandar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690843/
https://www.ncbi.nlm.nih.gov/pubmed/37947369
http://dx.doi.org/10.1021/acsnano.3c08456

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