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Metabolic signatures of cardiorenal dysfunction in plasma from sickle cell patients as a function of therapeutic transfusion and hydroxyurea treatment

Metabolomics studies in sickle cell disease (SCD) have been so far limited to tens of samples, owing to technical and experimental limitations. To overcome these limitations, we performed plasma metabolomics analyses on 596 samples from patients with SCD enrolled in the WALK-PHaSST study (clinicaltr...

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Detalles Bibliográficos
Autores principales: D’Alessandro, Angelo, Nouraie, S. Mehdi, Zhang, Yingze, Cendali, Francesca, Gamboni, Fabia, Reisz, Julie A., Zhang, Xu, Bartsch, Kyle W., Galbraith, Matthew D., Espinosa, Joaquin M., Gordeuk, Victor R., Gladwin, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690926/
https://www.ncbi.nlm.nih.gov/pubmed/37439373
http://dx.doi.org/10.3324/haematol.2023.283288