The enrichment of Fanconi anemia/homologous recombination pathway aberrations in ATM/ATR-mutated NSCLC was accompanied by unique molecular features and poor prognosis

BACKGROUND: ATM and ATR are two critical factors to regulate DNA damage response (DDR), and their mutations were frequently observed in different types of cancer, including non-small cell lung cancer (NSCLC). Given that the majority of identified ATM/ATR mutations were variants of uncertain signific...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Shi, Fangfang, Xu, Yang, Jiao, Yang, Zhang, Ying, Ou, Qiuxiang, Wu, Xue, Yang, Lingyi, Lai, Jinhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690992/
https://www.ncbi.nlm.nih.gov/pubmed/38041093
http://dx.doi.org/10.1186/s12967-023-04634-1

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