Cargando…
Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury
BACKGROUND: Prolonged hemodialysis (HD) is performed from 6 to 12 h and can last up to 24 h. To prevent system clotting some studies suggest that Regional Citrate Anticoagulation (RCA) use reduces bleeding rates relative to systemic heparin. However, there may be difficulties in the patient’s clinic...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691098/ https://www.ncbi.nlm.nih.gov/pubmed/38036951 http://dx.doi.org/10.1186/s12882-023-03342-8 |
_version_ | 1785152669659168768 |
---|---|
author | Vieira, Jorge Alberto Menegasso Reinheimer, Isabel Cristina dos Santos, Amanda Corrêa Halperin, Fernando Kowarick Susin, Luiza Aguirre Staub, Lia Portella Ribeiro, Raquel Jaqueline Eder da Silveira, Julia Braga Fontoura, Lucas Friedrich de Souza, Diego Candido Nunes, Karen Patrícia de Souza, Vandrea Carla da Silva Selistre, Luciano Poli-de-Figueiredo, Carlos Eduardo |
author_facet | Vieira, Jorge Alberto Menegasso Reinheimer, Isabel Cristina dos Santos, Amanda Corrêa Halperin, Fernando Kowarick Susin, Luiza Aguirre Staub, Lia Portella Ribeiro, Raquel Jaqueline Eder da Silveira, Julia Braga Fontoura, Lucas Friedrich de Souza, Diego Candido Nunes, Karen Patrícia de Souza, Vandrea Carla da Silva Selistre, Luciano Poli-de-Figueiredo, Carlos Eduardo |
author_sort | Vieira, Jorge Alberto Menegasso |
collection | PubMed |
description | BACKGROUND: Prolonged hemodialysis (HD) is performed from 6 to 12 h and can last up to 24 h. To prevent system clotting some studies suggest that Regional Citrate Anticoagulation (RCA) use reduces bleeding rates relative to systemic heparin. However, there may be difficulties in the patient’s clinical management and completing the prescribed HD with Genius system using RCA. OBJECTIVE: To analyze safety Quality Indicators (IQs) and follow up on prolonged HD with 4% sodium citrate solution in a Genius® hybrid system. METHODS: This is a retrospective cohort conducted in an intensive care unit. RESULTS: 53 random sessions of prolonged HD with 4% sodium citrate solution of critically ill patients with AKI assessed. Evaluated safety indicators were dysnatremia and metabolic alkalosis, observed in 15% and 9.4% of the sessions, respectively. Indicators of effectiveness were system clotting which occurred in 17.3%, and the minimum completion of the prescribed HD time, which was 75.5%. CONCLUSION: The assessment of the indicators showed that the use of RCA with a 4% sodium citrate solution in prolonged HD with the Genius system in critically ill patients with AKI can be performed in a simple, safe, and effective way. |
format | Online Article Text |
id | pubmed-10691098 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-106910982023-12-02 Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury Vieira, Jorge Alberto Menegasso Reinheimer, Isabel Cristina dos Santos, Amanda Corrêa Halperin, Fernando Kowarick Susin, Luiza Aguirre Staub, Lia Portella Ribeiro, Raquel Jaqueline Eder da Silveira, Julia Braga Fontoura, Lucas Friedrich de Souza, Diego Candido Nunes, Karen Patrícia de Souza, Vandrea Carla da Silva Selistre, Luciano Poli-de-Figueiredo, Carlos Eduardo BMC Nephrol Research BACKGROUND: Prolonged hemodialysis (HD) is performed from 6 to 12 h and can last up to 24 h. To prevent system clotting some studies suggest that Regional Citrate Anticoagulation (RCA) use reduces bleeding rates relative to systemic heparin. However, there may be difficulties in the patient’s clinical management and completing the prescribed HD with Genius system using RCA. OBJECTIVE: To analyze safety Quality Indicators (IQs) and follow up on prolonged HD with 4% sodium citrate solution in a Genius® hybrid system. METHODS: This is a retrospective cohort conducted in an intensive care unit. RESULTS: 53 random sessions of prolonged HD with 4% sodium citrate solution of critically ill patients with AKI assessed. Evaluated safety indicators were dysnatremia and metabolic alkalosis, observed in 15% and 9.4% of the sessions, respectively. Indicators of effectiveness were system clotting which occurred in 17.3%, and the minimum completion of the prescribed HD time, which was 75.5%. CONCLUSION: The assessment of the indicators showed that the use of RCA with a 4% sodium citrate solution in prolonged HD with the Genius system in critically ill patients with AKI can be performed in a simple, safe, and effective way. BioMed Central 2023-11-30 /pmc/articles/PMC10691098/ /pubmed/38036951 http://dx.doi.org/10.1186/s12882-023-03342-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Vieira, Jorge Alberto Menegasso Reinheimer, Isabel Cristina dos Santos, Amanda Corrêa Halperin, Fernando Kowarick Susin, Luiza Aguirre Staub, Lia Portella Ribeiro, Raquel Jaqueline Eder da Silveira, Julia Braga Fontoura, Lucas Friedrich de Souza, Diego Candido Nunes, Karen Patrícia de Souza, Vandrea Carla da Silva Selistre, Luciano Poli-de-Figueiredo, Carlos Eduardo Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury |
title | Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury |
title_full | Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury |
title_fullStr | Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury |
title_full_unstemmed | Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury |
title_short | Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury |
title_sort | quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691098/ https://www.ncbi.nlm.nih.gov/pubmed/38036951 http://dx.doi.org/10.1186/s12882-023-03342-8 |
work_keys_str_mv | AT vieirajorgealbertomenegasso qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT reinheimerisabelcristina qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT dossantosamandacorrea qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT halperinfernandokowarick qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT susinluizaaguirre qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT staubliaportella qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT ribeiroraqueljaquelineeder qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT dasilveirajuliabraga qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT fontouralucasfriedrich qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT desouzadiegocandido qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT nuneskarenpatricia qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT desouzavandreacarla qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT dasilvaselistreluciano qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury AT polidefigueiredocarloseduardo qualityindicatorsinprolongedhemodialysiswithregionalcitrateanticoagulationwiththegeniussystemretrospectivecohortofcriticalpatientswithacutekidneyinjury |