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Inhibition of miR-96-5p alleviates intervertebral disc degeneration by regulating the peroxisome proliferator-activated receptor γ/nuclear factor-kappaB pathway

BACKGROUND: Intervertebral disc degeneration (IDD) is the main pathogenesis of low back pain. MicroRNAs (miRNAs) have been found to exert regulatory function in IDD. This study aimed to investigate the effect and potential mechanism of miR-96-5p in IDD. METHODS: In vitro cell model of IDD was establ...

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Detalles Bibliográficos
Autores principales: Li, Xusheng, Hou, Qian, Yuan, Wenqi, Zhan, Xuehua, Yuan, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691123/
https://www.ncbi.nlm.nih.gov/pubmed/38041147
http://dx.doi.org/10.1186/s13018-023-04412-1