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HLA-DR genetic polymorphisms and hepatitis B virus mutations affect the risk of hepatocellular carcinoma in Han Chinese population

BACKGROUND: Human leucocyte antigen (HLA)-DR plays a crucial role in the immune response against hepatitis B virus (HBV). We aimed to investigate the associations of HLA-DR single nucleotide polymorphisms (SNPs) with the generation of hepatocellular carcinoma (HCC)-related HBV mutations. The effects...

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Detalles Bibliográficos
Autores principales: Zhao, Yubao, Chen, Kun, Yang, Hui, Zhang, Feng, Ding, Lu, Liu, Yan, Zhang, Le, Zhang, Yuchen, Wang, Huiliang, Deng, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691135/
https://www.ncbi.nlm.nih.gov/pubmed/38037048
http://dx.doi.org/10.1186/s12985-023-02253-2