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Comparing methods for constructing and representing human pangenome graphs

BACKGROUND: As a single reference genome cannot possibly represent all the variation present across human individuals, pangenome graphs have been introduced to incorporate population diversity within a wide range of genomic analyses. Several data structures have been proposed for representing collec...

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Detalles Bibliográficos
Autores principales: Andreace, Francesco, Lechat, Pierre, Dufresne, Yoann, Chikhi, Rayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691155/
https://www.ncbi.nlm.nih.gov/pubmed/38037131
http://dx.doi.org/10.1186/s13059-023-03098-2