Long-term Effects of IL-6 Receptor Blockade Therapy on Regulatory Lymphocytes and Neutrophils in Neuromyelitis Optica Spectrum Disorder

BACKGROUND AND OBJECTIVES: Neuromyelitis optica spectrum disorder (NMOSD) is a disabling autoimmune neurologic disease. Anti–IL-6 receptor (IL-6R) therapy prevents relapses in patients with anti–aquaporin 4 (AQP4)-IgG-positive NMOSD; however, it remains unclear how cellular immune components are alt...

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Detalles Bibliográficos
Autores principales: Matsuoka, Takako, Araki, Manabu, Lin, Youwei, Okamoto, Tomoko, Gold, Ralf, Chihara, Norio, Sato, Wakiro, Kimura, Atsuko, Tachimori, Hisateru, Miyamoto, Katsuichi, Kusunoki, Susumu, Yamamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691226/
https://www.ncbi.nlm.nih.gov/pubmed/37863660
http://dx.doi.org/10.1212/NXI.0000000000200173

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