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Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice

Gasdermins (GSDMs) share a common functional domain structure and are best known for their capacity to form membrane pores. These pores are hallmarks of a specific form of cell death called pyroptosis and mediate the secretion of pro-inflammatory cytokines such as interleukin 1β (IL1β) and interleuk...

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Detalles Bibliográficos
Autores principales: Fattinger, Stefan A., Maurer, Luca, Geiser, Petra, Bernard, Elliott M., Enz, Ursina, Ganguillet, Suwannee, Gül, Ersin, Kroon, Sanne, Demarco, Benjamin, Mack, Vanessa, Furter, Markus, Barthel, Manja, Pelczar, Pawel, Shao, Feng, Broz, Petr, Sellin, Mikael E., Hardt, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691232/
https://www.ncbi.nlm.nih.gov/pubmed/37988464
http://dx.doi.org/10.1073/pnas.2315503120