Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers

Background: Captisol(®)-enabled-fosphenytoin sodium (CE-fosphenytoin sodium) injection is a modified formulation of fosphenytoin sodium. Objective: We aim to compare the intravenous and intramuscular bioavailability and safety between CE-fosphenytoin sodium, fosphenytoin sodium (Cerebyx(®)), and phe...

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Detalles Bibliográficos
Autores principales: Li, Xiaojiao, Wu, Min, Sun, Jixuan, Jin, Weili, Han, Lei, Xu, Jia, Liu, Jingrui, Zhang, Hong, Wang, Jing, Wang, Daidi, Zhang, Hanyi, Zhang, Qing, Liu, Nini, Ding, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691362/
https://www.ncbi.nlm.nih.gov/pubmed/38044946
http://dx.doi.org/10.3389/fphar.2023.1204075

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