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Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment

Cancer, an intricate and multifaceted disease, is characterized by the uncontrolled proliferation of cells that can lead to serious health complications and ultimately death. Conventional therapeutic strategies mainly target rapidly dividing cancer cells, but often indiscriminately harm healthy cell...

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Autores principales: Singla, Madhav, Smriti, Gupta, Saurabh, Behal, Prateek, Singh, Sachin Kumar, Preetam, Subham, Rustagi, Sarvesh, Bora, Jutishna, Mittal, Pooja, Malik, Sumira, Slama, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691498/
https://www.ncbi.nlm.nih.gov/pubmed/38045808
http://dx.doi.org/10.3389/fnut.2023.1258516
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author Singla, Madhav
Smriti
Gupta, Saurabh
Behal, Prateek
Singh, Sachin Kumar
Preetam, Subham
Rustagi, Sarvesh
Bora, Jutishna
Mittal, Pooja
Malik, Sumira
Slama, Petr
author_facet Singla, Madhav
Smriti
Gupta, Saurabh
Behal, Prateek
Singh, Sachin Kumar
Preetam, Subham
Rustagi, Sarvesh
Bora, Jutishna
Mittal, Pooja
Malik, Sumira
Slama, Petr
author_sort Singla, Madhav
collection PubMed
description Cancer, an intricate and multifaceted disease, is characterized by the uncontrolled proliferation of cells that can lead to serious health complications and ultimately death. Conventional therapeutic strategies mainly target rapidly dividing cancer cells, but often indiscriminately harm healthy cells in the process. As a result, there is a growing interest in exploring novel therapies that are both effective and less toxic to normal cells. Herbs have long been used as natural remedies for various diseases and conditions. Some herbal compounds exhibit potent anti-cancer properties, making them potential candidates for nutraceutical-based treatments. However, despite their promising efficacy, there are considerable limitations in utilizing herbal preparations due to their poor solubility, low bioavailability, rapid metabolism and excretion, as well as potential interference with other medications. Nanotechnology offers a unique platform to overcome these challenges by encapsulating herbal compounds within nanoparticles. This approach not only increases solubility and stability but also enhances the cellular uptake of nutraceuticals, allowing for controlled and targeted delivery of therapeutic agents directly at tumor sites. By harnessing the power of nanotechnology-enabled therapy, this new frontier in cancer treatment presents an opportunity to minimize toxicity while maximizing efficacy. In conclusion, this manuscript provides compelling evidence for integrating nanotechnology with nutraceuticals derived from herbal sources to optimize cancer therapy outcomes. We explore the roadblocks associated with traditional herbal treatments and demonstrate how nanotechnology can help circumvent these issues, paving the way for safer and more effective cancer interventions in future oncological practice.
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spelling pubmed-106914982023-12-02 Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment Singla, Madhav Smriti Gupta, Saurabh Behal, Prateek Singh, Sachin Kumar Preetam, Subham Rustagi, Sarvesh Bora, Jutishna Mittal, Pooja Malik, Sumira Slama, Petr Front Nutr Nutrition Cancer, an intricate and multifaceted disease, is characterized by the uncontrolled proliferation of cells that can lead to serious health complications and ultimately death. Conventional therapeutic strategies mainly target rapidly dividing cancer cells, but often indiscriminately harm healthy cells in the process. As a result, there is a growing interest in exploring novel therapies that are both effective and less toxic to normal cells. Herbs have long been used as natural remedies for various diseases and conditions. Some herbal compounds exhibit potent anti-cancer properties, making them potential candidates for nutraceutical-based treatments. However, despite their promising efficacy, there are considerable limitations in utilizing herbal preparations due to their poor solubility, low bioavailability, rapid metabolism and excretion, as well as potential interference with other medications. Nanotechnology offers a unique platform to overcome these challenges by encapsulating herbal compounds within nanoparticles. This approach not only increases solubility and stability but also enhances the cellular uptake of nutraceuticals, allowing for controlled and targeted delivery of therapeutic agents directly at tumor sites. By harnessing the power of nanotechnology-enabled therapy, this new frontier in cancer treatment presents an opportunity to minimize toxicity while maximizing efficacy. In conclusion, this manuscript provides compelling evidence for integrating nanotechnology with nutraceuticals derived from herbal sources to optimize cancer therapy outcomes. We explore the roadblocks associated with traditional herbal treatments and demonstrate how nanotechnology can help circumvent these issues, paving the way for safer and more effective cancer interventions in future oncological practice. Frontiers Media S.A. 2023-11-17 /pmc/articles/PMC10691498/ /pubmed/38045808 http://dx.doi.org/10.3389/fnut.2023.1258516 Text en Copyright © 2023 Singla, Smriti, Gupta, Behal, Singh, Preetam, Rustagi, Bora, Mittal, Malik and Slama. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Singla, Madhav
Smriti
Gupta, Saurabh
Behal, Prateek
Singh, Sachin Kumar
Preetam, Subham
Rustagi, Sarvesh
Bora, Jutishna
Mittal, Pooja
Malik, Sumira
Slama, Petr
Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment
title Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment
title_full Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment
title_fullStr Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment
title_full_unstemmed Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment
title_short Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment
title_sort unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691498/
https://www.ncbi.nlm.nih.gov/pubmed/38045808
http://dx.doi.org/10.3389/fnut.2023.1258516
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