Cargando…

Viability of the virtual cone technique using a fixed small multi‐leaf collimator field for stereotactic radiosurgery of trigeminal neuralgia

Dosimetric uncertainties in very small (≤1.5 × 1.5 cm(2)) photon fields are remarkably higher, which undermines the validity of the virtual cone (VC) technique with a diminutive and variable MLC fields. We evaluate the accuracy and reproducibility of the VC method with a very small, fixed MLC field...

Descripción completa

Detalles Bibliográficos
Autores principales: Neupane, Taindra, Shang, Charles, Kassel, Maxwell, Muhammad, Wazir, Leventouri, Theodora, Williams, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691631/
https://www.ncbi.nlm.nih.gov/pubmed/37722766
http://dx.doi.org/10.1002/acm2.14148
_version_ 1785152774846021632
author Neupane, Taindra
Shang, Charles
Kassel, Maxwell
Muhammad, Wazir
Leventouri, Theodora
Williams, Timothy R.
author_facet Neupane, Taindra
Shang, Charles
Kassel, Maxwell
Muhammad, Wazir
Leventouri, Theodora
Williams, Timothy R.
author_sort Neupane, Taindra
collection PubMed
description Dosimetric uncertainties in very small (≤1.5 × 1.5 cm(2)) photon fields are remarkably higher, which undermines the validity of the virtual cone (VC) technique with a diminutive and variable MLC fields. We evaluate the accuracy and reproducibility of the VC method with a very small, fixed MLC field setting, called a fixed virtual cone (fVC), for small target radiosurgery such as trigeminal neuralgia (TGN). The fVC is characterized by 0.5 cm x 0.5 cm high‐definition (HD) MLC field of 10MV FFF beam defined at 100 cm SAD, while backup jaws are positioned at 1.5 cm x 1.5 cm. A spherical dose distribution equivalent to 5 mm (diameter) physical cone was generated using 10–14 non‐coplanar, partial arcs. Dosimetric accuracy was validated using SRS diode (PTW 60018), SRS MapCHECK (SNC) measurements. As a quality assurance measure, 10 treatment plans (SRS) for TGN, consisting of various arc ranges at different collimator angles were analyzed using 6 MV FFF and 10 MV FFF beams, including a field‐by‐field study (n = 130 fields). Dose outputs were compared between the Eclipse TPS and measurements (SRS MapCHECK). Moreover, dosimetric changes in the field defining fVC, prompted by a minute (± 0.5–1.0 mm) leaf shift, was examined among TPS, diode measurements, and Monte Carlo (MC) simulations. The beam model for fVC was validated (≤3% difference) using SRS MapCHECK based absolute dose measurements. The equivalent diameters of the 50% isodose distribution were found comparable to that of a 5 mm cone. Additionally, the comparison of field output factors, dose per MU between the TPS and SRS diode measurements using the fVC field, including ± 1 mm leaf shift, yielded average discrepancies within 5.5% and 3.5% for 6 MV FFF and 10 MV FFF beams, respectively. Overall, the fVC method is a credible alternative to the physical cone (5 mm) that can be applied in routine radiosurgical treatment of TGN.
format Online
Article
Text
id pubmed-10691631
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-106916312023-12-02 Viability of the virtual cone technique using a fixed small multi‐leaf collimator field for stereotactic radiosurgery of trigeminal neuralgia Neupane, Taindra Shang, Charles Kassel, Maxwell Muhammad, Wazir Leventouri, Theodora Williams, Timothy R. J Appl Clin Med Phys Radiation Oncology Physics Dosimetric uncertainties in very small (≤1.5 × 1.5 cm(2)) photon fields are remarkably higher, which undermines the validity of the virtual cone (VC) technique with a diminutive and variable MLC fields. We evaluate the accuracy and reproducibility of the VC method with a very small, fixed MLC field setting, called a fixed virtual cone (fVC), for small target radiosurgery such as trigeminal neuralgia (TGN). The fVC is characterized by 0.5 cm x 0.5 cm high‐definition (HD) MLC field of 10MV FFF beam defined at 100 cm SAD, while backup jaws are positioned at 1.5 cm x 1.5 cm. A spherical dose distribution equivalent to 5 mm (diameter) physical cone was generated using 10–14 non‐coplanar, partial arcs. Dosimetric accuracy was validated using SRS diode (PTW 60018), SRS MapCHECK (SNC) measurements. As a quality assurance measure, 10 treatment plans (SRS) for TGN, consisting of various arc ranges at different collimator angles were analyzed using 6 MV FFF and 10 MV FFF beams, including a field‐by‐field study (n = 130 fields). Dose outputs were compared between the Eclipse TPS and measurements (SRS MapCHECK). Moreover, dosimetric changes in the field defining fVC, prompted by a minute (± 0.5–1.0 mm) leaf shift, was examined among TPS, diode measurements, and Monte Carlo (MC) simulations. The beam model for fVC was validated (≤3% difference) using SRS MapCHECK based absolute dose measurements. The equivalent diameters of the 50% isodose distribution were found comparable to that of a 5 mm cone. Additionally, the comparison of field output factors, dose per MU between the TPS and SRS diode measurements using the fVC field, including ± 1 mm leaf shift, yielded average discrepancies within 5.5% and 3.5% for 6 MV FFF and 10 MV FFF beams, respectively. Overall, the fVC method is a credible alternative to the physical cone (5 mm) that can be applied in routine radiosurgical treatment of TGN. John Wiley and Sons Inc. 2023-09-18 /pmc/articles/PMC10691631/ /pubmed/37722766 http://dx.doi.org/10.1002/acm2.14148 Text en © 2023 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Neupane, Taindra
Shang, Charles
Kassel, Maxwell
Muhammad, Wazir
Leventouri, Theodora
Williams, Timothy R.
Viability of the virtual cone technique using a fixed small multi‐leaf collimator field for stereotactic radiosurgery of trigeminal neuralgia
title Viability of the virtual cone technique using a fixed small multi‐leaf collimator field for stereotactic radiosurgery of trigeminal neuralgia
title_full Viability of the virtual cone technique using a fixed small multi‐leaf collimator field for stereotactic radiosurgery of trigeminal neuralgia
title_fullStr Viability of the virtual cone technique using a fixed small multi‐leaf collimator field for stereotactic radiosurgery of trigeminal neuralgia
title_full_unstemmed Viability of the virtual cone technique using a fixed small multi‐leaf collimator field for stereotactic radiosurgery of trigeminal neuralgia
title_short Viability of the virtual cone technique using a fixed small multi‐leaf collimator field for stereotactic radiosurgery of trigeminal neuralgia
title_sort viability of the virtual cone technique using a fixed small multi‐leaf collimator field for stereotactic radiosurgery of trigeminal neuralgia
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691631/
https://www.ncbi.nlm.nih.gov/pubmed/37722766
http://dx.doi.org/10.1002/acm2.14148
work_keys_str_mv AT neupanetaindra viabilityofthevirtualconetechniqueusingafixedsmallmultileafcollimatorfieldforstereotacticradiosurgeryoftrigeminalneuralgia
AT shangcharles viabilityofthevirtualconetechniqueusingafixedsmallmultileafcollimatorfieldforstereotacticradiosurgeryoftrigeminalneuralgia
AT kasselmaxwell viabilityofthevirtualconetechniqueusingafixedsmallmultileafcollimatorfieldforstereotacticradiosurgeryoftrigeminalneuralgia
AT muhammadwazir viabilityofthevirtualconetechniqueusingafixedsmallmultileafcollimatorfieldforstereotacticradiosurgeryoftrigeminalneuralgia
AT leventouritheodora viabilityofthevirtualconetechniqueusingafixedsmallmultileafcollimatorfieldforstereotacticradiosurgeryoftrigeminalneuralgia
AT williamstimothyr viabilityofthevirtualconetechniqueusingafixedsmallmultileafcollimatorfieldforstereotacticradiosurgeryoftrigeminalneuralgia