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Knockout of Matrix Metalloproteinase 2 Opposes Hypertension- and Diabetes-induced Nephropathy
The progression of chronic kidney disease results from the accumulation of extracellular matrix leading to end-stage renal disease. We previously demonstrated that a broad-spectrum matrix metalloproteinase (MMP) inhibitor reduced renal injury in rat models of hypertension and diabetes. However, the...
Autores principales: | Hirata, Takashi, Fan, Fan, Fan, Letao, Amin, Ghadir, White, Tiffani, Geurts, Aron M., Kojima, Naoki, Takahashi, Teisuke, Miyata, Noriyuki, Williams, Jan, Roman, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Cardiovascular Pharmacology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691661/ https://www.ncbi.nlm.nih.gov/pubmed/37643020 http://dx.doi.org/10.1097/FJC.0000000000001473 |
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