Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP

BACKGROUND: Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters in plasma from high density lipoprotein (HDL) to very low density lipoprotein and low density lipoprotein. Loss-of-function variants in the CETP gene cause elevated levels of HDL cholesterol. In this study, we have de...

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Detalles Bibliográficos
Autores principales: Ølnes, Åsa Schawlann, Teigen, Marianne, Laerdahl, Jon K., Leren, Trond P., Strøm, Thea Bismo, Bjune, Katrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691695/
https://www.ncbi.nlm.nih.gov/pubmed/38039300
http://dx.doi.org/10.1371/journal.pone.0294764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691695/
https://www.ncbi.nlm.nih.gov/pubmed/38039300
http://dx.doi.org/10.1371/journal.pone.0294764

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