A medium-chain fatty acid analogue prevents hepatosteatosis and decreases inflammatory lipid metabolites in a murine model of parenteral nutrition-induced hepatosteatosis

BACKGROUND: Parenteral (intravenous) nutrition is lifesaving for patients with intestinal failure, but long-term use of parenteral nutrition often leads to liver disease. SEFA-6179 is a synthetic medium-chain fatty acid analogue designed to target multiple fatty acid receptors regulating metabolic a...

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Detalles Bibliográficos
Autores principales: Cho, Bennet S., Fligor, Scott C., Fell, Gillian L., Secor, Jordan D., Tsikis, Savas T., Pan, Amy, Yu, Lumeng J., Ko, Victoria H., Dao, Duy T., Anez-Bustillos, Lorenzo, Hirsch, Thomas I., Lund, Jenny, Rustan, Arild C., Fraser, David A., Gura, Kathleen M., Puder, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691711/
https://www.ncbi.nlm.nih.gov/pubmed/38039287
http://dx.doi.org/10.1371/journal.pone.0295244

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