Silencing of topical proline hydroxylase domain 2 promotes the healing of rat diabetic wounds by phosphorylating AMPK

BACKGROUND: For diabetic ulcers, the impaired response to hypoxia is a key feature associated with delayed healing. In the early phase of hypoxia, hypoxic signaling activates the AMPK system through direct phosphorylation of the PHD2 pathway, producing a significant endogenous hypoxic protective eff...

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Detalles Bibliográficos
Autores principales: Xie, Defu, Liu, Mengchang, Lin, Yingxi, Liu, Xingke, Yan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691724/
https://www.ncbi.nlm.nih.gov/pubmed/38039326
http://dx.doi.org/10.1371/journal.pone.0294566

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