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X-nuclear MRS and MRI on a standard clinical proton-only MRI scanner
In light of the growing interest in-vivo deuterium metabolic imaging, hyperpolarized (13)C, (15)N, (3)He, and (129)Xe imaging, as well as (31)P spectroscopy and imaging in large animals on clinical MR scanners, we demonstrate the use of a (radio)frequency converter system to allow X-nuclear MR spect...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691785/ https://www.ncbi.nlm.nih.gov/pubmed/38046796 http://dx.doi.org/10.1016/j.jmro.2023.100118 |
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author | Yen, Yi-Fen Takahashi, Atsushi M. Ackerman, Jerome L. |
author_facet | Yen, Yi-Fen Takahashi, Atsushi M. Ackerman, Jerome L. |
author_sort | Yen, Yi-Fen |
collection | PubMed |
description | In light of the growing interest in-vivo deuterium metabolic imaging, hyperpolarized (13)C, (15)N, (3)He, and (129)Xe imaging, as well as (31)P spectroscopy and imaging in large animals on clinical MR scanners, we demonstrate the use of a (radio)frequency converter system to allow X-nuclear MR spectroscopy (MRS) and MR imaging (MRI) on standard clinical MRI scanners without multinuclear capability. This is not only an economical alternative to the multinuclear system (MNS) provided by the scanner vendors, but also overcomes the frequency bandwidth problem of some vendor-provided MNSs that prohibit users from applications with X-nuclei of low magnetogyric ratio, such as deuterium (6.536 MHz/Tesla) and (15)N (−4.316 MHz/Tesla). Here we illustrate the design of the frequency converter system and demonstrate its feasibility for (31)P (17.235 MHz/Tesla), (13)C (10.708 MHz/Tesla), and (15)N MRS and MRI on a clinical MRI scanner without vendor-provided multinuclear hardware. |
format | Online Article Text |
id | pubmed-10691785 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
record_format | MEDLINE/PubMed |
spelling | pubmed-106917852023-12-01 X-nuclear MRS and MRI on a standard clinical proton-only MRI scanner Yen, Yi-Fen Takahashi, Atsushi M. Ackerman, Jerome L. J Magn Reson Open Article In light of the growing interest in-vivo deuterium metabolic imaging, hyperpolarized (13)C, (15)N, (3)He, and (129)Xe imaging, as well as (31)P spectroscopy and imaging in large animals on clinical MR scanners, we demonstrate the use of a (radio)frequency converter system to allow X-nuclear MR spectroscopy (MRS) and MR imaging (MRI) on standard clinical MRI scanners without multinuclear capability. This is not only an economical alternative to the multinuclear system (MNS) provided by the scanner vendors, but also overcomes the frequency bandwidth problem of some vendor-provided MNSs that prohibit users from applications with X-nuclei of low magnetogyric ratio, such as deuterium (6.536 MHz/Tesla) and (15)N (−4.316 MHz/Tesla). Here we illustrate the design of the frequency converter system and demonstrate its feasibility for (31)P (17.235 MHz/Tesla), (13)C (10.708 MHz/Tesla), and (15)N MRS and MRI on a clinical MRI scanner without vendor-provided multinuclear hardware. 2023-12 2023-04-24 /pmc/articles/PMC10691785/ /pubmed/38046796 http://dx.doi.org/10.1016/j.jmro.2023.100118 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ). |
spellingShingle | Article Yen, Yi-Fen Takahashi, Atsushi M. Ackerman, Jerome L. X-nuclear MRS and MRI on a standard clinical proton-only MRI scanner |
title | X-nuclear MRS and MRI on a standard clinical proton-only MRI scanner |
title_full | X-nuclear MRS and MRI on a standard clinical proton-only MRI scanner |
title_fullStr | X-nuclear MRS and MRI on a standard clinical proton-only MRI scanner |
title_full_unstemmed | X-nuclear MRS and MRI on a standard clinical proton-only MRI scanner |
title_short | X-nuclear MRS and MRI on a standard clinical proton-only MRI scanner |
title_sort | x-nuclear mrs and mri on a standard clinical proton-only mri scanner |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691785/ https://www.ncbi.nlm.nih.gov/pubmed/38046796 http://dx.doi.org/10.1016/j.jmro.2023.100118 |
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