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EGF-Receptor against Amphiregulin (AREG) Influences Costimulatory Molecules on Monocytes and T Cells and Modulates T-Cell Responses

Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR) and has been shown to regulate the phagocytosis-induced cell death of monocytes in peripheral blood. AREG-dependent apoptotic signaling engages factors of the intrinsic and extrinsic apoptotic pathway, such as BCL-2, BCL-...

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Detalles Bibliográficos
Autores principales: Dreschers, Stephan, Platen, Christopher, Oppermann, Louise, Doughty, Caitlin, Ludwig, Andreas, Babendreyer, Aaron, Orlikowsky, Thorsten W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691888/
https://www.ncbi.nlm.nih.gov/pubmed/38046264
http://dx.doi.org/10.1155/2023/8883045