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Subgraph extraction and graph representation learning for single cell Hi-C imputation and clustering

Single-cell Hi-C (scHi-C) technology enables the investigation of 3D chromatin structure variability across individual cells. However, the analysis of scHi-C data is challenged by a large number of missing values. Here, we present a scHi-C data imputation model HiC-SGL, based on Subgraph extraction...

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Detalles Bibliográficos
Autores principales:	Zheng, Jiahao, Yang, Yuedong, Dai, Zhiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Problem Solving Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691963/ https://www.ncbi.nlm.nih.gov/pubmed/38040494 http://dx.doi.org/10.1093/bib/bbad379

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