Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade immune-elimination

Cancer stem cells (CSCs), being the primary contributors in tumor initiation, metastasis, and relapse, ought to have seminal roles in evasion of immune surveillance. Tumor-promoting CD4(+)CD25(+)FOXP3(+ )T-regulatory cells (Tregs) have been described to abolish host defense mechanisms by impeding th...

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Detalles Bibliográficos
Autores principales: Mukherjee, Sumon, Chakraborty, Sourio, Basak, Udit, Pati, Subhadip, Dutta, Apratim, Dutta, Saikat, Roy, Dia, Banerjee, Shruti, Ray, Arpan, Sa, Gaurisankar, Das, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692020/
https://www.ncbi.nlm.nih.gov/pubmed/38038865
http://dx.doi.org/10.1007/s12672-023-00787-z

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