Rhein methotrexate-decorated solid lipid nanoparticles altering adjuvant arthritis progression through endoplasmic reticulum stress-mediated apoptosis

Methotrexate (MTX) and diacerein (DIA) are two of the most potent disease-modifying anti-rheumatic drugs used for the treatment of rheumatoid arthritis (RA). DIA has reflected some GIT and hepatobiliary manifestations in numerous cases. It undergoes biotransformation in the liver into the active met...

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Detalles Bibliográficos
Autores principales: El-Refaie, Wessam M., Ghazy, Mostafa S., Ateyya, Fady A., Sheta, Eman, Shafek, Mohanad Y., Ibrahim, Mahmoud S., Ismail, Mahmoud MA., Gowayed, Mennatallah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692035/
https://www.ncbi.nlm.nih.gov/pubmed/37526838
http://dx.doi.org/10.1007/s10787-023-01295-w

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