Enhanced oxidative phosphorylation, re-organized intracellular signaling, and epigenetic de-silencing as revealed by oligodendrocyte translatome analysis after contusive spinal cord injury

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Reducing the loss of oligodendrocytes (OLs) is a major goal for neuroprotection after spinal cord injury (SCI). Therefore, the OL translatome was determined in Ribotag:Plp1-CreERT2 mice at 2, 10, and 42 days after moderate contusive T9 SCI. At 2 and 42 days, mitochondrial respiration- or actin cytos...

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Detalles Bibliográficos
Autores principales: Forston, Michael D., Wei, George Z., Chariker, Julia H., Stephenson, Tyler, Andres, Kariena, Glover, Charles, Rouchka, Eric C., Whittemore, Scott R., Hetman, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692148/
https://www.ncbi.nlm.nih.gov/pubmed/38040794
http://dx.doi.org/10.1038/s41598-023-48425-6
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