Fructose overconsumption impairs hepatic manganese homeostasis and ammonia disposal

Arginase, a manganese (Mn)-dependent enzyme, is indispensable for urea generation and ammonia disposal in the liver. The potential role of fructose in Mn and ammonia metabolism is undefined. Here we demonstrate that fructose overconsumption impairs hepatic Mn homeostasis and ammonia disposal in male...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Jian-Hui, Chen, Yu-Xia, Feng, Yingying, Yang, Xiaohang, Lin, Jie, Wang, Ting, Wei, Chun-Chun, Ma, Xian-Hua, Yang, Rui, Cao, Dongmei, Zhang, Hai, Xie, Xiangyang, Xie, Zhifang, Zhang, Weiping J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692208/
https://www.ncbi.nlm.nih.gov/pubmed/38040719
http://dx.doi.org/10.1038/s41467-023-43609-0

Ejemplares similares

Ejemplares similares